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Anti-APE1 Rabbit Monoclonal Antibody

Boster Bio Anti-APE1 Rabbit Monoclonal Antibody catalog # M00627-3. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3; NR4A1; GFRP1, HMR, NAK1

Gene Name

APEX1

Gene ID

328

UniProt

P27695

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human APE1

Clonality

Monoclonal

Clone

Clone: 17A44

Tissue Specificity

Fetal muscle and adult liver, brain and thyroid.

Applications

WB, IHC

Field of Research

Apoptosis, Cancer, Cell Biology, Cell Death, Co-Activators/Co-Repressors, Epigenetics and Nuclear Signaling, Invasion/Microenvironment, Nuclear Receptors, Nuclear Signaling Pathways, Nucleus

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3' (By similarity) . May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

64463 MW

Observed Molecular Weight

36 kDa

Gene Name Synonym

Nuclear receptor subfamily 4 group A member 1

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

T-cell surface glycoprotein CD4

Isotype

IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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