Anti-p57 Kip2 Rabbit Monoclonal Antibody
Boster Bio Anti-p57 Kip2 Rabbit Monoclonal Antibody catalog # M01244-2. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD62P; SELP; GMRP, GRMP
Gene Name
CDKN1C
Gene ID
1028
UniProt
P49918
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human p57 Kip2
Clonality
Monoclonal
Clone
Clone: 17C19
Tissue Specificity
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Applications
WB, IHC, ICC, IF, IP
Field of Research
Adaptive Immunity, Angiogenesis, Atherosclerosis, Cardiovascular, Cell Adhesion Molecules, Cell Type Markers, Hematopoietic Progenitors, Immunology, Myeloid, Platelets, Stem Cells, Vascular Inflammation
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Ca (2+) -dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
90834 MW
Observed Molecular Weight
80 kDa
Gene Name Synonym
P-selectin
Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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