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Anti-ABHD5 Monoclonal Antibody

Boster Bio Anti-ABHD5 Monoclonal Antibody catalog # M03209. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Glutamine synthetase; GS;6.3.1.2; Glutamate decarboxylase;4.1.1.15; Glutamate--ammonia ligase; GLUL; GLNS

Gene Name

ABHD5

Gene ID

51099

UniProt

Q8WTS1

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human ABHD5 Lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation.

Clonality

Monoclonal

Clone

Clone: AFHE-1

Tissue Specificity

In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. .

Applications

WB, IHC, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Cardiovascular, Fatty Acid Oxidation, Fatty Acids, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Obesity, Pathways and Processes, Redox Metabolism, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity) . Essential for proliferation of fetal skin fibroblasts. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

42064 MW

Observed Molecular Weight

34 kDa

Gene Name Synonym

Glutamine synthetase

Subcellular Location

Cytoplasm. Mitochondrion .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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