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Anti-IBA1 AIF1 Monoclonal Antibody

Boster Bio Anti-IBA1 AIF1 Monoclonal Antibody catalog # M01394-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Retinal dehydrogenase 1; RALDH 1; RalDH1;1.2.1.36; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; ALDH1A1; ALDC, ALDH1, PUMB1

Gene Name

AIF1

Gene ID

199

UniProt

P55008

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IBA1

Clonality

Monoclonal

Clone

Clone: AFGH-1

Tissue Specificity

Highly expressed in thymus, spleen and bone marrow compared to non-hematopoietic tissues such as small intestine, liver, or kidney tissues. Colocalizes with GSK3B and TAU in the Alzheimer disease (AD) brain. Elevated levels seen in breast and colon carcinomas, and which correlates with tumor progression and invasiveness or risk of progression. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Actin Binding Proteins, Actin, etc., Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

54862 MW

Observed Molecular Weight

120-140 kDa

Gene Name Synonym

Retinal dehydrogenase 1

Subcellular Location

Cytoplasm.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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