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Anti-CA125 / MUC16 Monoclonal Antibody

Boster Bio Anti-CA125 / MUC16 Monoclonal Antibody catalog # M01641-1. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Mucin-16 ; MUC-16; Ovarian cancer-related tumor marker CA125 ; CA-125 ; Ovarian carcinoma antigen CA125 ; MUC16 ; CA125

Gene Name

MUC16

Gene ID

94025

UniProt

Q8WXI7

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CA-125 (MUC16) Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Clonality

Monoclonal

Clone

Clone: AFFO-13

Tissue Specificity

Expressed in corneal and conjunctival epithelia (at protein level) . Overexpressed in ovarian carcinomas and ovarian low malignant potential (LMP) tumors as compared to the expression in normal ovarian tissue and ovarian adenomas. .

Applications

WB, IHC

Field of Research

Cancer, Cell Type Markers, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Invasion/Microenvironment, Signal Transduction, Tags & Cell Markers, Tumor Antigens, Tumor Associated, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

1519175 MW

Observed Molecular Weight

80 kDa

Gene Name Synonym

Mucin-16

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Secreted, extracellular space. May be liberated into the extracellular space following the phosphorylation of the intracellular C-terminus which induces the proteolytic cleavage and liberation of the extracellular domain.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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