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Anti-MUC5B Monoclonal Antibody

Boster Bio Anti-MUC5B Monoclonal Antibody catalog # M00719. Tested in WB, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1; Proapolipoprotein A-I; ProapoA-I; Truncated apolipoprotein A-I; Apolipoprotein A-I (1-242) ; APOA1

Gene Name

MUC5B

Gene ID

727897

UniProt

Q9HC84

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human MUC5B

Clonality

Monoclonal

Clone

Clone: AFCO-13

Tissue Specificity

Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.

Applications

WB, Flow Cytometry

Field of Research

Cell Biology, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT) . As part of the SPAP complex, activates spermatozoa motility.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30778 MW

Observed Molecular Weight

37 kDa

Gene Name Synonym

Apolipoprotein A1

Subcellular Location

Secreted.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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