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Anti-IGHD Monoclonal Antibody

Boster Bio Anti-IGHD Monoclonal Antibody catalog # M05183. Tested in WB, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF7L1; TCF3

Gene Name

IGHD

Gene ID

3495

UniProt

P01880

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IGHD There are two named isoforms of IGHD produced by alternative splicing, a secreted form and a single pass type I membrane protein.

Clonality

Monoclonal

Clone

Clone: AFBO-9

Tissue Specificity

Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium. .

Applications

WB, IHC

Field of Research

Immunoglobulins, Immunology

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity) . Down-regulates NQO1, leading to increased mitomycin c resistance. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

62631 MW

Observed Molecular Weight

14 kDa

Gene Name Synonym

Transcription factor 7-like 1

Subcellular Location

Nucleus.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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