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Anti-Calsequestrin 1 Monoclonal Antibody

Boster Bio Anti-Calsequestrin 1 Monoclonal Antibody catalog # M05235. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Histone deacetylase 10; HD10;3.5.1.98; HDAC10

Gene Name

CASQ1

Gene ID

844

UniProt

P31415

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Calsequestrin 1 Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium. Also binds laminin.

Clonality

Monoclonal

Clone

Clone: AEGE-3

Tissue Specificity

Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Applications

WB, IHC, Flow Cytometry

Field of Research

Calcium Binding Proteins, Calcium Signaling, Cancer, Cardiovascular, ER Proteins, Metabolism, Protein Trafficking, Signal Transduction, Signaling Pathway

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

71445 MW

Observed Molecular Weight

65 kDa

Gene Name Synonym

Histone deacetylase 10

Subcellular Location

Cytoplasm. Nucleus. Excluded from the nucleoli.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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