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Anti-Geminin Monoclonal Antibody

Boster Bio Anti-Geminin Monoclonal Antibody catalog # M06060. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human.

Product Specifications

Synonyms

Hyaluronan and proteoglycan link protein 1; Cartilage-linking protein 1; Cartilage-link protein; Proteoglycan link protein; HAPLN1; CRTL1

Gene Name

GMNN

Gene ID

51053

UniProt

O75496

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Geminin Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.

Clonality

Monoclonal

Clone

Clone: AEGO-7

Tissue Specificity

Widely expressed. Weakly expressed in the brain. .

Applications

WB, IHC, ICC, IF

Field of Research

Cancer, Cell Cycle, Cell Division, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

40166 MW

Observed Molecular Weight

63 kDa

Gene Name Synonym

Hyaluronan and proteoglycan link protein 1

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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