Anti-RBPJK Monoclonal Antibody
Boster Bio Anti-RBPJK Monoclonal Antibody catalog # M00767. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Moesin; Membrane-organizing extension spike protein; MSN
Gene Name
RBPJ
Gene ID
3516
UniProt
Q06330
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human RBPJK Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins.
Clonality
Monoclonal
Clone
Clone: AEEF-18
Tissue Specificity
In all tissues and cultured cells studied.
Applications
WB, ICC, IF
Field of Research
2339, Epigenetics and Nuclear Signaling, Neurology Process, Neuroscience, Nuclear, Signaling Pathways, Stem Cells, Transcription, Transcription Factors
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
67820 MW
Observed Molecular Weight
15 kDa
Gene Name Synonym
Moesin
Subcellular Location
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity) . Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. .
Protein Name
T-cell surface glycoprotein CD4
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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