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Anti-PSD93 Monoclonal Antibody

Boster Bio Anti-PSD93 Monoclonal Antibody catalog # M04826. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Alpha-sarcoglycan; Alpha-SG;50 kDa dystrophin-associated glycoprotein;50DAG; Adhalin; Dystroglycan-2; SGCA; ADL, DAG2

Gene Name

DLG2

Gene ID

1740

UniProt

Q15700

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PSD93 Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels.

Clonality

Monoclonal

Clone

Clone: AEAC-4

Tissue Specificity

Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.

Applications

WB, IP, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Carbohydrate Metabolism, Cardiovascular, Cholesterol Metabolism, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Of Carbohydrates, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Obesity, Pathways and Processes, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

42875 MW

Observed Molecular Weight

66 kDa

Gene Name Synonym

Alpha-sarcoglycan

Subcellular Location

Cell membrane, sarcolemma ; Single-pass type I membrane protein . Cytoplasm, cytoskeleton .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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