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Anti-BAG2 Monoclonal Antibody

Boster Bio Anti-BAG2 Monoclonal Antibody catalog # M04933. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis; BBC3; PUMA

Gene Name

BAG2

Gene ID

9532

UniProt

O95816

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human BAG2 Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release.

Clonality

Monoclonal

Clone

Clone: AEOE-2

Tissue Specificity

Ubiquitously expressed. .

Applications

WB, ICC, IF

Field of Research

Metabolism, Pathways and Processes, Signal Transduction, Apoptosis, Cancer, Cell Biology, Intracellular, Cell Death, Metabolism Processes, Protein Trafficking, Chaperones, Invasion/Microenvironment, Apoptotic Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

20532 MW

Observed Molecular Weight

61-80 kDa

Gene Name Synonym

Bcl-2-binding component 3

Subcellular Location

Mitochondrion . Localized to the mitochondria in order to induce cytochrome c release.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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