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Anti-Cullin 3 Monoclonal Antibody

Boster Bio Anti-Cullin 3 Monoclonal Antibody catalog # M00747. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

G2/mitotic-specific cyclin-B1; CCNB1; CCNB

Gene Name

CUL3

Gene ID

8452

UniProt

Q13618

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cullin 3 Core component of multiple cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

Clonality

Monoclonal

Clone

Clone: AEOD-3

Tissue Specificity

Ubiquitous. Expressed at high levels in testis.

Applications

WB, IP, Flow Cytometry

Field of Research

Apoptosis, Cancer, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Cell Death, Nucleus, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, SCF Complex E3 Ligase, Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Essential for the control of the cell cycle at the G2/M (mitosis) transition. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

48337 MW

Observed Molecular Weight

133 kDa

Gene Name Synonym

G2/mitotic-specific cyclin-B1

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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