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Anti-Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Monoclonal Antibody

Selected Variant

MP01723

Size: 100 µL/Vial

Boster Bio Anti-Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Monoclonal Antibody catalog # MP01723. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Phospho Site

S474, S560, S602

Synonyms

Red fluorescent protein eqFP611; GFP-like chromoprotein

Gene Name

PAK4

Gene ID

106821730

UniProt

O96013/Q9P286/Q9NQU5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Phospho-PAK4 + PAK5 + PAK6 (S474 + S560 + S602) Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival.

Clonality

Monoclonal

Clone

Clone: ADFF-16

Tissue Specificity

Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC) . Levels rapidly diminish as soon as ESC's differentiate (at protein levels) . Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .

Applications

WB, Flow Cytometry

Field of Research

Actin, Actin, etc., Apoptosis, Cancer, Cell Biology, Cell Cycle, Cytoskeleton, Cytoskeleton/ECM, Intracellular, Kinases, Kinases/Phosphatases, Microfilaments, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Pigment protein. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

26053 MW

Observed Molecular Weight

15 kDa

Gene Name Synonym

Red fluorescent protein eqFP611

Subcellular Location

Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction. .

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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