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Anti-USP13 Monoclonal Antibody

Boster Bio Anti-USP13 Monoclonal Antibody catalog # M07816. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ubiquitin-like-conjugating enzyme ATG10;6.3.2.-; Autophagy-related protein 10; APG10-like; ATG10; APG10L; PP12616

Gene Name

USP13

Gene ID

8975

UniProt

Q92995

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human USP13 Mediates deubiquitination of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability.

Clonality

Monoclonal

Clone

Clone: ADDG-21

Tissue Specificity

Brain.

Applications

WB, ICC, IF, IP, Flow Cytometry

Field of Research

Cell Biology, Chromatin Modifying Enzymes, Deubiquitination, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity) . Plays a role in adenovirus-mediated cell lysis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

25279 MW

Observed Molecular Weight

83 kDa

Gene Name Synonym

Ubiquitin-like-conjugating enzyme ATG10

Subcellular Location

Cytoplasm .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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