Anti-USP22 Monoclonal Antibody
Boster Bio Anti-USP22 Monoclonal Antibody catalog # M03887. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.
Product Specifications
Synonyms
Bcl-2-related protein A1; Bcl-2-like protein 5; Bcl2-L-5; Hemopoietic-specific early response protein; Protein BFL-1; Protein GRS; BCL2A1; BCL2L5, BFL1, GRS, HBPA1
Gene Name
USP22
Gene ID
23326
UniProt
Q9UPT9
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human USP22 Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator.
Clonality
Monoclonal
Clone
Clone: ADCG-21
Tissue Specificity
Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
Applications
WB, ICC, IF, IP, Flow Cytometry
Field of Research
Cell Biology, Chromatin Modifying Enzymes, Deubiquitination, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ub-Like Proteins
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity) . Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
20132 MW
Observed Molecular Weight
29 kDa
Gene Name Synonym
Bcl-2-related protein A1
Subcellular Location
Cytoplasm.
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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