Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CTLA4 (CD152) Monoclonal Antibody

Boster Bio Anti-CTLA4 (CD152) Monoclonal Antibody catalog # M00020. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF

Gene Name

CTLA4

Gene ID

1493

UniProt

P16410

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human CTLA4 (CD152)

Clonality

Monoclonal

Clone

Clone: ADCD-3

Tissue Specificity

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

WB, ICC, IF

Field of Research

Adaptive Immunity, Autoimmune, Hematopoietic Progenitors, Immune System Diseases, Immunology, Lymphoid, Non-CD, Stem Cells, T Cells, T Lymphocytic Lineage

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) - responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

88068 MW

Observed Molecular Weight

120 kDa

Gene Name Synonym

Signal transducer and activator of transcription 3

Subcellular Location

Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rat P2RY1 shRNA Plasmid
abx984880-01 150 µg

Rat P2RY1 shRNA Plasmid

Sign In for Pricing
View Details
Rat P2RY1 shRNA Plasmid
abx984880-02 300 µg

Rat P2RY1 shRNA Plasmid

Sign In for Pricing
View Details
GM2AP1 3'UTR GFP Stable Cell Line
TU058945 1.0 mL

GM2AP1 3'UTR GFP Stable Cell Line

Sign In for Pricing
View Details
3’,4’-Dibenzyloxy-1-phenyl-2-butanone
TRC-D418015-100MG 100 mg

3’,4’-Dibenzyloxy-1-phenyl-2-butanone

Sign In for Pricing
View Details
PPP1R12C sgRNA CRISPR Lentivector (Human) (Target 3)
K1705404 1.0 µg DNA

PPP1R12C sgRNA CRISPR Lentivector (Human) (Target 3)

Sign In for Pricing
View Details
Mouse Atp Binding Cassette Transporter A1 ABCA1 ELISA Kit
BG-MUS10192 1 Each

Mouse Atp Binding Cassette Transporter A1 ABCA1 ELISA Kit

Sign In for Pricing
View Details