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Anti-Cytochrome P450 2D6 CYP2D6 Monoclonal Antibody

Boster Bio Anti-Cytochrome P450 2D6 CYP2D6 Monoclonal Antibody catalog # M00498. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

NAD (P) H dehydrogenase [quinone] 1;1.6.5.2; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD (P) H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1; NQO1; DIA4, NMOR1

Gene Name

CYP2D6

Gene ID

1565

UniProt

P10635

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human Cytochrome P450 2D6 Cytochrome P450 2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.

Clonality

Monoclonal

Clone

Clone: ADBO-3

Tissue Specificity

Duodenum and pancreas (Langerhans islet beta cells and small subsets of endocrine non-beta-cells, at low levels in acinar cells) .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Metabolism, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

30868 MW

Observed Molecular Weight

52 kDa

Gene Name Synonym

NAD (P) H dehydrogenase [quinone] 1

Subcellular Location

Cytoplasm.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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