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Anti-NDRG1 Monoclonal Antibody

Boster Bio Anti-NDRG1 Monoclonal Antibody catalog # M01327-1. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Thrombomodulin; TM; Fetomodulin; CD141; THBD; THRM

Gene Name

NDRG1

Gene ID

10397

UniProt

Q92597

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human NDRG1 May have a growth inhibitory role.

Clonality

Monoclonal

Clone

Clone: ADOE-14

Tissue Specificity

Endothelial cells are unique in synthesizing thrombomodulin.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Angiogenesis, Cancer, Cancer Susceptibility, Epigenetics and Nuclear Signaling, Invasion/Microenvironment, Neural Signal Transduction, Neurodegenerative Disease, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Proto-Oncogenes, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

60329 MW

Observed Molecular Weight

105 kDa

Gene Name Synonym

Thrombomodulin

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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