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Anti-PMP22 Monoclonal Antibody

Boster Bio Anti-PMP22 Monoclonal Antibody catalog # M00890. Tested in WB application. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Apoptotic protease-activating factor 1; APAF-1; APAF1; KIAA0413

Gene Name

PMP22

Gene ID

5376

UniProt

Q01453

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human PMP22

Clonality

Monoclonal

Clone

Clone: ACIC-16

Tissue Specificity

Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.

Applications

WB

Field of Research

Cell Adhesion Proteins, Cell Type Marker, Cell Type Markers, Membrane Proteins, Neuroscience, Tags & Cell Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

141840 MW

Observed Molecular Weight

52 kDa

Gene Name Synonym

Apoptotic protease-activating factor 1

Subcellular Location

Cytoplasm .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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