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Anti-Slit2 Monoclonal Antibody

Boster Bio Anti-Slit2 Monoclonal Antibody catalog # M01627. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Tryptophan 5-hydroxylase 1;1.14.16.4; Tryptophan 5-monooxygenase 1; TPH1; TPH, TPRH, TRPH

Gene Name

SLIT2

Gene ID

9353

UniProt

O94813

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Slit2 Thought to act as molecular guidance cue in cellular migration, and function appears to be mediated by interaction with roundabout homolog receptors.

Clonality

Monoclonal

Clone

Clone: ACGF-19

Tissue Specificity

Isoform 2 seems to be less widely expressed than isoform 1.

Applications

WB, IHC, IP

Field of Research

Axonal Guidance Proteins, Growth and Development, Neural Signal Transduction, Neurology Process, Neuroscience

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

T-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

50985 MW

Observed Molecular Weight

43 kDa

Gene Name Synonym

Tryptophan 5-hydroxylase 1

Subcellular Location

Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor. Cell junction, synapse, synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity) . .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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