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Anti-p23 Monoclonal Antibody

Boster Bio Anti-p23 Monoclonal Antibody catalog # M04136. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

MIC

Gene Name

PTGES3

Gene ID

10728

UniProt

Q15185

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human p23 Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.

Clonality

Monoclonal

Clone

Clone: ACAH-16

Tissue Specificity

Ubiquitous. Expressed in numerous tumor cell lines, especially in bladder tumor cells. .

Applications

WB, ICC, IF, IP

Field of Research

Cancer, Cancer Metabolism, Chaperones, Chromosome Structure, Endocrine Metabolism, Epigenetics and Nuclear Signaling, Heat Shock Proteins, Hormone Biosynthesis, Lipid Metabolism, Metabolic Signaling Pathway, Metabolism, Pathways and Processes, Protein Trafficking, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

83678 MW

Observed Molecular Weight

47 kDa

Gene Name Synonym

MICOS complex subunit MIC60

Subcellular Location

Mitochondrion inner membrane ; Single-pass membrane protein . Mitochondrion .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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