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Anti-ZAP70 Monoclonal Antibody

Boster Bio Anti-ZAP70 Monoclonal Antibody catalog # M00754-3. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

G2/mitotic-specific cyclin-B1; CCNB1; CCNB

Gene Name

ZAP70

Gene ID

7535

UniProt

P43403

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human ZAP70 The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.

Clonality

Monoclonal

Clone

Clone: ACAF-26

Tissue Specificity

Ubiquitous. Expressed at high levels in testis.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Adaptive Immunity, Cell Type Markers, Immunology, Protein Phosphorylation, Signal Transduction, T Cells, Tags & Cell Markers, Tumor Associated, Tyrosine Kinases

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Essential for the control of the cell cycle at the G2/M (mitosis) transition. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

48337 MW

Observed Molecular Weight

100 kDa

Gene Name Synonym

G2/mitotic-specific cyclin-B1

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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