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Anti-TBPL1 Monoclonal Antibody

Boster Bio Anti-TBPL1 Monoclonal Antibody catalog # M07468. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Trophoblast glycoprotein;5T4 oncofetal antigen;5T4 oncofetal trophoblast glycoprotein;5T4 oncotrophoblast glycoprotein; M6P1; Wnt-activated inhibitory factor 1; WAIF1; TPBG;5T4

Gene Name

TBPL1

Gene ID

9519

UniProt

P62380

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human TBPL1 Does not bind the TATA box. Has DNA-binding ability.

Clonality

Monoclonal

Clone

Clone: ACOI-20

Tissue Specificity

Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

RNA Polymerase, Transcription

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

May function as an inhibitor of Wnt/beta-catenin signaling by inly interacting with LRP6 and blocking Wnt3a- dependent LRP6 internalization. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

46032 MW

Observed Molecular Weight

80 kDa

Gene Name Synonym

Trophoblast glycoprotein

Subcellular Location

Cell membrane ; Single-pass type I membrane protein .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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