Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ErbB2 (HER2) Monoclonal Antibody

Boster Bio Anti-ErbB2 (HER2) Monoclonal Antibody catalog # M00010-1. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human.

Product Specifications

Synonyms

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF

Gene Name

ERBB2

Gene ID

2064

UniProt

P04626

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human ErbB2 (HER2) .

Clonality

Monoclonal

Clone

Clone: BCI-5

Tissue Specificity

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Tumor Associated, Tumor Biomarkers, Tumor Immunology, Tumor-Associated Antigens, Tyrosine Kinases

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) - responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

88068 MW

Observed Molecular Weight

54 kDa

Gene Name Synonym

Signal transducer and activator of transcription 3

Subcellular Location

Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ULK1 (phospho-Ser757) rabbit pAb
E44H14625 100 µL

ULK1 (phospho-Ser757) rabbit pAb

Sign In for Pricing
View Details
Rabbit Polyclonal UBXD2 Antibody [Alexa Fluor 700]
NBP3-18404AF700 0.1 mL

Rabbit Polyclonal UBXD2 Antibody [Alexa Fluor 700]

Sign In for Pricing
View Details
PKC α (r) -PR
sc-108089-PR 10 µM - 20 µL

PKC α (r) -PR

Sign In for Pricing
View Details
NSE gamma Antibody / ENO2 / Gamma Enolase
V5451-20UG 20 µg

NSE gamma Antibody / ENO2 / Gamma Enolase

Sign In for Pricing
View Details
Lentiviral mouse Gramd1a shRNA (UAS) - Lentiviral mouse Gramd1a shRNA (UAS) (25)
GTR15164537 1 Vial

Lentiviral mouse Gramd1a shRNA (UAS) - Lentiviral mouse Gramd1a shRNA (UAS) (25)

Sign In for Pricing
View Details
PacBlue Anti-human CD2 Antibody *RPA-2.10*
100211J0-AAT 100 Tests

PacBlue Anti-human CD2 Antibody *RPA-2.10*

Sign In for Pricing
View Details