What is the catalog number for Anti-ERK2 Monoclonal Antibody?

The catalog number for Anti-ERK2 Monoclonal Antibody is M00030.

What sizes are available for Anti-ERK2 Monoclonal Antibody?

Anti-ERK2 Monoclonal Antibody is available in the following size(s): 100 µL/Vial.

Is Anti-ERK2 Monoclonal Antibody in stock?

Anti-ERK2 Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-ERK2 Monoclonal Antibody?

The safety data sheet for Anti-ERK2 Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M00030.

Anti-ERK2 Monoclonal Antibody

Boster Bio Anti-ERK2 Monoclonal Antibody catalog # M00030. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF

Gene Name

MAPK1

Gene ID

5594

UniProt

P28482

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human ERK2 Act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.

Clonality

Monoclonal

Clone

Clone: II-13

Tissue Specificity

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) - responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

88068 MW

Observed Molecular Weight

131 kDa

Gene Name Synonym

Signal transducer and activator of transcription 3

Subcellular Location

Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3. Identified in a complex with LYN and PAG1.

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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Anti-ERK2 Monoclonal Antibody

Product Specifications

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Immunogen

Clonality

Clone

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Function

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

Frequently Asked Questions

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