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Anti-Wilms Tumor Protein WT1 Rabbit Monoclonal Antibody

Boster Bio Anti-Wilms Tumor Protein WT1 Rabbit Monoclonal Antibody catalog # M00199-1. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Wilms tumor protein; WT33; WT1

Gene Name

WT1

Gene ID

7490

UniProt

P19544

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Wilms Tumor Protein

Clonality

Monoclonal

Clone

Clone: CEH-23

Tissue Specificity

Expressed in the kidney and a subset of hematopoietic cells.

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Lymphoid, Myeloid, Signal Transduction, Stem Cells, T Lymphocytic Lineage

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

49188 MW

Observed Molecular Weight

103 kDa

Gene Name Synonym

Wilms tumor protein

Subcellular Location

Nucleus. Nucleus, nucleolus. Cytoplasm . Shuttles between nucleus and cytoplasm. .

Protein Name

P2X purinoceptor 1

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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