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Anti-Integrin alpha 2 ITGA2 Rabbit Monoclonal Antibody

Boster Bio Anti-Integrin alpha 2 ITGA2 Rabbit Monoclonal Antibody catalog # M01933. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b; ITGA2; CD49B

Gene Name

ITGA2

Gene ID

3673

UniProt

P17301

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Integrin alpha 2

Clonality

Monoclonal

Clone

Clone: GEB-9

Tissue Specificity

Widely expressed with highest levels in muscle, heart, placenta and spinal cord.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Cell Adhesion, Cytoskeleton/ECM, Integrins, Metabolism, Metabolism Processes, Pathways and Processes, Response To Hypoxia, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

129295 MW

Observed Molecular Weight

17 kDa

Gene Name Synonym

Integrin alpha-2

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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