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Anti-Integrin beta 4 ITGB4 Rabbit Monoclonal Antibody

Boster Bio Anti-Integrin beta 4 ITGB4 Rabbit Monoclonal Antibody catalog # M01015. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Integrin beta-4; GP150; CD104; ITGB4

Gene Name

ITGB4

Gene ID

3691

UniProt

P16144

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human Integrin beta 4

Clonality

Monoclonal

Clone

Clone: AAFE-9

Tissue Specificity

Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.

Applications

WB, IHC

Field of Research

Cell Adhesion, Cytoskeleton/ECM, Integrins, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

202167 MW

Observed Molecular Weight

240 kDa

Gene Name Synonym

Integrin beta-4

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Colocalizes with DST at the leading edge of migrating keratinocytes.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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