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Anti-Cytokeratin 18 Krt18 Rabbit Monoclonal Antibody

Boster Bio Anti-Cytokeratin 18 Krt18 Rabbit Monoclonal Antibody catalog # M01357-2. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Keratin, type I cytoskeletal 18; Cytokeratin endo B; Keratin D; Cytokeratin-18; CK-18; Keratin-18; K18; Krt18; Kerd, Krt1-18

Gene Name

Krt18

Gene ID

3875

UniProt

P05783

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cytokeratin 18

Clonality

Monoclonal

Clone

Clone: GBF-11

Tissue Specificity

Expressed in endoderm, intestinal epithelial cells and in most extraembryonic tissues. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Intermediate Filaments, Microtubules, Signal Transduction, Structures, Tumor Associated

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

47538 MW

Observed Molecular Weight

48 kDa

Gene Name Synonym

Keratin, type I cytoskeletal 18

Subcellular Location

Nucleus matrix . Nucleus, nucleolus . Cytoplasm .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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