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Anti-Calcineurin A Rabbit Monoclonal Antibody

Boster Bio Anti-Calcineurin A Rabbit Monoclonal Antibody catalog # M03026. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform;3.1.3.16; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform; PPP3CA; CALNA, CNA

Gene Name

PPP3CA

Gene ID

5530

UniProt

Q08209

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Calcineurin A

Clonality

Monoclonal

Clone

Clone: ABOG-16

Tissue Specificity

Expressed in adult and fetal heart, brain, liver, lung, skeletal muscle, and kidney. Also expressed in testis and placenta. Highest levels in adult brain, placenta, lung, kidney, and testis. Expressed in hormone responsive tissues, including normal and cancerous mammary, ovarian and prostate epithelium. .

Applications

WB, ICC, IF, Flow Cytometry

Field of Research

Cancer, Cancer Metabolism, Cardiovascular, Epigenetics and Nuclear Signaling, Hypoxia, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes, Response To Hypoxia

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

58688 MW

Observed Molecular Weight

59 kDa

Gene Name Synonym

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

Subcellular Location

Cell membrane . Cell membrane, sarcolemma . Nucleus . Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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