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Anti-14-3-3 Theta YWHAQ Rabbit Monoclonal Antibody

Boster Bio Anti-14-3-3 Theta YWHAQ Rabbit Monoclonal Antibody catalog # M03904. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

14-3-3 protein theta;14-3-3 protein T-cell;14-3-3 protein tau; Protein HS1; YWHAQ

Gene Name

YWHAQ

Gene ID

10971

UniProt

P27348

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human 14-3-3 Theta

Clonality

Monoclonal

Clone

Clone: HHF-25

Tissue Specificity

Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Histones

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

27764 MW

Observed Molecular Weight

35 kDa

Gene Name Synonym

14-3-3 protein theta

Subcellular Location

Cytoplasm. In neurons, axonally transported to the nerve terminals.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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