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Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

Boster Bio Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody catalog # M01127. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin; SFN; HME1

Gene Name

SFN

Gene ID

2810

UniProt

P31947

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthesized peptide derived from human 14-3-3 sigma

Clonality

Monoclonal

Clone

Clone: HBB-19

Tissue Specificity

Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Applications

WB, IHC

Field of Research

Adapters, Cell Type Marker, Cytoplasmic, Neural Signal Transduction, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Signaling Pathways, Stem Cells, Synapse Marker

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

27774 MW

Observed Molecular Weight

80 kDa

Gene Name Synonym

14-3-3 protein sigma

Subcellular Location

Cytoplasm. Nucleus . Secreted. May be secreted by a non-classical secretory pathway.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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