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Anti-KMT4 / Dot1L Rabbit Monoclonal Antibody

Boster Bio Anti-KMT4 / Dot1L Rabbit Monoclonal Antibody catalog # M00840. Tested in IHC, WB application. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Histone-lysine N-methyltransferase, H3 lysine-79 specific;2.1.1.43; DOT1-like protein; Histone H3-K79 methyltransferase; H3-K79-HMTase; Lysine N-methyltransferase 4; DOT1L; KIAA1814, KMT4

Gene Name

DOT1L

Gene ID

84444

UniProt

Q8TEK3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A synthesized peptide derived from human KMT4 / Dot1L

Clonality

Monoclonal

Clone

Clone: CBF-4

Tissue Specificity

KMT4 / Dot1L Antibody detects endogenous levels of total KMT4 / Dot1L

Applications

WB, IHC

Field of Research

Chromatin Modifying Enzymes, DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling, Methylation

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

184853 MW

Observed Molecular Weight

68 kDa

Gene Name Synonym

Histone-lysine N-methyltransferase, H3 lysine-79 specific

Subcellular Location

Nucleus .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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