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Anti-Histone H2A HIST1H2AB Rabbit Monoclonal Antibody

Boster Bio Anti-Histone H2A HIST1H2AB Rabbit Monoclonal Antibody catalog # M16777-2. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Histone H2A type 1-B/E; Histone H2A.2; Histone H2A/a; Histone H2A/m; HIST1H2AB; H2AFM; HIST1H2AE; H2AFA

Gene Name

HIST1H2AB

Gene ID

3012

UniProt

P04908

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Histone H2A

Clonality

Monoclonal

Clone

Clone: DFA-8

Tissue Specificity

Widely expressed with highest levels in brain, kidney and muscle. .

Applications

WB, IHC, ICC, IF

Field of Research

Epigenetics and Nuclear Signaling, Histones

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

14135 MW

Observed Molecular Weight

37 kDa

Gene Name Synonym

Histone H2A type 1-B/E

Subcellular Location

Nucleus. Chromosome.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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