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Anti-CD3 epsilon Rabbit Monoclonal Antibody

Boster Bio Anti-CD3 epsilon Rabbit Monoclonal Antibody catalog # M02675-1. Tested in IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e; CD3E; T3E

Gene Name

CD3E

Gene ID

916

UniProt

P07766

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human CD3 epsilon

Clonality

Monoclonal

Clone

Clone: COB-3

Tissue Specificity

Expressed in monocytes, basophils, B-cells, umbilical vein endothelial cells (HUVEC) and B-lymphoblastoid cells. Lower expression detected in CD4+ T-lymphocytes and natural killer cells. In the brain, detected in endothelial cells and capillaries, and in mature neurons of the frontal cortex and hippocampus. Expressed in tubular formation in the kidney. Highly expressed in astroglial tumor endothelial, microglial and glioma cells. Expressed at low levels in normal CD34+ progenitor cells, but at very high levels in several myeloid malignant cell lines. Expressed in breast carcinomas but not in normal breast tissue (at protein level) . .

Applications

IHC, ICC, IF, IP

Field of Research

Adaptive Immunity, Hematopoietic Progenitors, Immunology, Stem Cells, T Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

The CD3 complex mediates signal transduction.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

250 kDa

Gene Name Synonym

T-cell surface glycoprotein CD3 epsilon chain

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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