Anti-Annexin A2 ANXA2 Rabbit Monoclonal Antibody

Boster Bio Anti-Annexin A2 ANXA2 Rabbit Monoclonal Antibody catalog # M00868. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; Placental anticoagulant protein IV; PAP-IV; Protein I; p36; ANXA2; ANX2, ANX2L4, CAL1H, LPC2D

Gene Name

ANXA2

Gene ID

302

UniProt

P07355

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Annexin A2

Clonality

Monoclonal

Clone

Clone: ABDG-1

Tissue Specificity

Detected in erythrocytes (at protein level) . Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. .

Applications

WB, IHC, ICC, IF, Flow Cytometry

Field of Research

Channels, Metabolism, Plasma Membrane, Signal Transduction, Vitamins/Minerals

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

38604 MW

Observed Molecular Weight

45 kDa

Gene Name Synonym

Annexin A2

Subcellular Location

Secreted, extracellular space, extracellular matrix, basement membrane . Melanosome . In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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Anti-Annexin A2 ANXA2 Rabbit Monoclonal Antibody

Product Specifications

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Immunogen

Clonality

Clone

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Function

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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