Anti-ERR alpha Rabbit Monoclonal Antibody
Boster Bio Anti-ERR alpha Rabbit Monoclonal Antibody catalog # M03339. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Steroid hormone receptor ERR1; Estrogen receptor-like 1; Estrogen-related receptor alpha; ERR-alpha; Nuclear receptor subfamily 3 group B member 1; ESRRA; ERR1, ESRL1, NR3B1
Gene Name
ESRRA
Gene ID
2101
UniProt
P11474
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human ERR alpha
Clonality
Monoclonal
Clone
Clone: EIO-5
Tissue Specificity
Visceral organs specific expression. Strong expression was found in liver, kidney and intestine followed by spleen and to a lesser extent the adrenals.
Applications
WB, IP, Flow Cytometry
Field of Research
Cancer, Domain Families, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Signaling Pathways, Nucleotide Metabolism, Pathways and Processes, Signal Transduction, Signaling Pathway, Transcription, Zinc Finger
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
45510 MW
Observed Molecular Weight
60 kDa
Gene Name Synonym
Steroid hormone receptor ERR1
Subcellular Location
Nucleus .
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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