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Anti-GRP78 BiP HSPA5 Rabbit Monoclonal Antibody

Boster Bio Anti-GRP78 BiP HSPA5 Rabbit Monoclonal Antibody catalog # M00955-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca (2+) -binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP; HSPA5; GRP78

Gene Name

HSPA5

Gene ID

3309

UniProt

P11021

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human GRP78 BiP

Clonality

Monoclonal

Clone

Clone: AII-8

Tissue Specificity

Expressed in the excretory system, thyroid gland and Wilms tumors.

Applications

WB, IHC

Field of Research

Organelles, Subcellular Markers, Tags & Cell Markers

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

72333 MW

Observed Molecular Weight

28 kDa

Gene Name Synonym

78 kDa glucose-regulated protein

Subcellular Location

Endoplasmic reticulum lumen. Melanosome. Cytoplasm . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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