Anti-IKB beta Rabbit Monoclonal Antibody
Boster Bio Anti-IKB beta Rabbit Monoclonal Antibody catalog # M05766. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.
Product Specifications
Synonyms
NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9; NFKBIB; IKBB, TRIP9
Gene Name
NFKBIB
Gene ID
4793
UniProt
Q15653
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human IKB beta
Clonality
Monoclonal
Clone
Clone: FDH-14
Tissue Specificity
Expressed in all tissues examined.
Applications
WB, IHC, ICC, IF, IP
Field of Research
Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, TLR Signaling
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
37771 MW
Observed Molecular Weight
30 kDa
Gene Name Synonym
NF-kappa-B inhibitor beta
Subcellular Location
Cytoplasm . Nucleus .
Protein Name
T-cell surface glycoprotein CD3 zeta chain
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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