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Anti-IKB beta Rabbit Monoclonal Antibody

Boster Bio Anti-IKB beta Rabbit Monoclonal Antibody catalog # M05766. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9; NFKBIB; IKBB, TRIP9

Gene Name

NFKBIB

Gene ID

4793

UniProt

Q15653

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human IKB beta

Clonality

Monoclonal

Clone

Clone: FDH-14

Tissue Specificity

Expressed in all tissues examined.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, NFKB Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, TLR Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

37771 MW

Observed Molecular Weight

30 kDa

Gene Name Synonym

NF-kappa-B inhibitor beta

Subcellular Location

Cytoplasm . Nucleus .

Protein Name

T-cell surface glycoprotein CD3 zeta chain

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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