Anti-Vinculin VCL Rabbit Monoclonal Antibody

Boster Bio Anti-Vinculin VCL Rabbit Monoclonal Antibody catalog # M01207. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Vinculin; Metavinculin; MV; VCL

Gene Name

VCL

Gene ID

7414

UniProt

P18206

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Vinculin

Clonality

Monoclonal

Clone

Clone: AIG-22

Tissue Specificity

Metavinculin is muscle-specific.

Applications

IP, IF, IHC, ICC, WB

Field of Research

Actin Binding Proteins, Actin, etc., Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Actin filament (F-actin) -binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

123799 MW

Observed Molecular Weight

17 kDa

Gene Name Synonym

Vinculin

Subcellular Location

Cytoplasm, cytoskeleton . Cell junction, adherens junction . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, focal adhesion . Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity) . Colocalizes with LIMD1 in the focal adhesions. .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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Anti-Vinculin VCL Rabbit Monoclonal Antibody

Product Specifications

Synonyms

Gene Name

Gene ID

UniProt

Host

Reactivity

Immunogen

Clonality

Clone

Tissue Specificity

Applications

Field of Research

Purification

Concentration

Form

Function

Storage Conditions

Calculated Molecular Weight

Observed Molecular Weight

Gene Name Synonym

Subcellular Location

Protein Name

Isotype

Contents

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