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Anti-RALBP1 Rabbit Monoclonal Antibody

Boster Bio Anti-RALBP1 Rabbit Monoclonal Antibody catalog # M01403. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

RalA-binding protein 1; RalBP1;76 kDa Ral-interacting protein; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; RALBP1; RLIP1, RLIP76

Gene Name

RALBP1

Gene ID

10928

UniProt

Q15311

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human RALBP1

Clonality

Monoclonal

Clone

Clone: FDI-18

Tissue Specificity

Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. .

Applications

WB, IHC, Flow Cytometry

Field of Research

Adapters, Apoptosis, Associated Proteins, Cell Biology, Cytoplasmic, Immunology, Innate Immunity, Intracellular, Kinases, Signal Transduction, TLR Signaling

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

76063 MW

Observed Molecular Weight

30-50 kDa

Gene Name Synonym

RalA-binding protein 1

Subcellular Location

Membrane ; Peripheral membrane protein .

Protein Name

Glycogen synthase kinase-3 beta (gsk3b)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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