Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody
Boster Bio Anti-NR5A2/Lrh 1 Rabbit Monoclonal Antibody catalog # M01332. Tested in WB application. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Nuclear receptor subfamily 5 group A member 2; Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1; NR5A2; B1F, CPF, FTF
Gene Name
NR5A2
Gene ID
2494
UniProt
O00482
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human NR5A2
Clonality
Monoclonal
Clone
Clone: ABHO-14
Tissue Specificity
Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells.
Applications
WB
Field of Research
Developmental Biology, Embryogenesis, Embryonic Stem Cells, Epigenetics and Nuclear Signaling, Host-Virus Interaction, Interspecies Interaction, Intracellular, Microbiology, Stem Cells, Surface Molecules, Transcription
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
61331 MW
Observed Molecular Weight
105 kDa
Gene Name Synonym
Nuclear receptor subfamily 5 group A member 2
Subcellular Location
Nucleus .
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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