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Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody

Boster Bio Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody catalog # M00595. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Histone deacetylase 6; HD6;3.5.1.98; HDAC6; KIAA0901; JM21

Gene Name

HDAC6

Gene ID

10013

UniProt

Q9UBN7

Host

Rabbit

Reactivity

Human

Immunogen

A synthesized peptide derived from human HDAC6

Clonality

Monoclonal

Clone

Clone: HEE-8

Tissue Specificity

T-cells and endothelial cells.

Applications

WB, IHC, ICC, IF, IP

Field of Research

Acetylation, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Signaling Pathways, Stem Cells

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity) . Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

131419 MW

Observed Molecular Weight

160 kDa

Gene Name Synonym

Histone deacetylase 6

Subcellular Location

Nucleus. Cytoplasm. Perikaryon . Cell projection, dendrite . Cell projection, axon . It is mainly cytoplasmic, where it is associated with microtubules.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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