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Anti-IL1RA Rabbit Monoclonal Antibody

Boster Bio Anti-IL1RA Rabbit Monoclonal Antibody catalog # M00651. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Interleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; ICIL-1RA; IL1 inhibitor; Anakinra; IL1RN; IL1F3, IL1RA

Gene Name

IL1RN

Gene ID

3557

UniProt

P18510

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human IL1RA

Clonality

Monoclonal

Clone

Clone: GEI-9

Tissue Specificity

The intracellular form of IL1RN is predominantly expressed in epithelial cells.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Cytokines, Immunology, Innate Immunity, Interleukins

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

20055 MW

Observed Molecular Weight

42 kDa

Gene Name Synonym

Interleukin-1 receptor antagonist protein

Subcellular Location

Isoform 1: Secreted.

Protein Name

T-cell surface glycoprotein CD4

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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