Anti-Bcl10 Rabbit Monoclonal Antibody
Boster Bio Anti-Bcl10 Rabbit Monoclonal Antibody catalog # M01616-1. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human.
Product Specifications
Synonyms
B-cell lymphoma/leukemia 10; B-cell CLL/lymphoma 10; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; CIPER; Cellular homolog of vCARMEN; cCARMEN; Cellular-E10; c-E10; Mammalian CARD-containing adapter molecule E10; mE10; BCL10; CIPER, CLAP
Gene Name
BCL10
Gene ID
8915
UniProt
O95999
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human Bcl10
Clonality
Monoclonal
Clone
Clone: GDB-2
Tissue Specificity
Ubiquitous.
Applications
WB, IHC, ICC, IF, IP
Field of Research
Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, NFKB Pathway, Nuclear Signaling, Pathways and Processes, Signal Transduction, Signaling Pathway
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
Involved in adaptive immune response (PubMed:25365219) . Promotes apoptosis, pro-caspase-9 maturation and activation of NF- kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 (PubMed:18264101) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
26252 MW
Observed Molecular Weight
65 kDa
Gene Name Synonym
B-cell lymphoma/leukemia 10
Subcellular Location
Cytoplasm, perinuclear region . Membrane raft . Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts.
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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