Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody
Boster Bio Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody catalog # M30950-2. Tested in WB, IHC applications. This antibody reacts with Human.
Product Specifications
Synonyms
Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein; EGP; Epithelial glycoprotein 314; EGP314; hEGP314; KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; CD326; EPCAM; GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Gene Name
EPCAM
Gene ID
4072
UniProt
P16422
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human EpCAM
Clonality
Monoclonal
Clone
Clone: GBG-5
Tissue Specificity
Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC) . Levels rapidly diminish as soon as ESC's differentiate (at protein levels) . Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .
Applications
WB, IHC
Field of Research
Cell Type Markers, Tags & Cell Markers, Tumor Associated
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Form
Liquid
Function
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
34932 MW
Observed Molecular Weight
50 kDa
Gene Name Synonym
Epithelial cell adhesion molecule
Subcellular Location
Lateral cell membrane ; Single-pass type I membrane protein . Cell junction, tight junction . Colocalizes with CLDN7 at the lateral cell membrane and tight junction. .
Isotype
Rabbit IgG
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
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