Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Rad18 Rabbit Monoclonal Antibody

Boster Bio Anti-Rad18 Rabbit Monoclonal Antibody catalog # M01622. Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase RAD18;6.3.2.-; Postreplication repair protein RAD18; hHR18; hRAD18; RING finger protein 73; RAD18; RNF73

Gene Name

RAD18

Gene ID

56852

UniProt

Q9NS91

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Rad18

Clonality

Monoclonal

Clone

Clone: FFC-18

Tissue Specificity

Expressed ubiquitously in normal tissues.

Applications

WB, Flow Cytometry

Field of Research

Cell Biology,2339, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ring Finger E3 Ligase, Ubiquitin E3 Enzymes

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap- filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono- ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

56223 MW

Observed Molecular Weight

28 kDa

Gene Name Synonym

E3 ubiquitin-protein ligase RAD18

Subcellular Location

Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Associates with chromatin (PubMed:25931565) . Colocalizes with SLF1 in the nucleus and to centrosomes (PubMed:15632077) . Relocalizes with SLF1 to nuclear foci in response to DNA damage (PubMed:22036607) . Accumulates with the SLF1-SLF2 and SMC5-SMC6 complexes at replication-coupled DNA interstrand repair and DNA double-strand breaks (DSBs) sites on chromatin in a ubiquitin-dependent manner (PubMed:25931565) . .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Chymase 1, Mast Cell (CMA1)
MBS2097527-01 0.01 mg

Recombinant Chymase 1, Mast Cell (CMA1)

Ask
View Details
Recombinant Chymase 1, Mast Cell (CMA1)
MBS2097527-02 0.05 mg

Recombinant Chymase 1, Mast Cell (CMA1)

Ask
View Details
Recombinant Chymase 1, Mast Cell (CMA1)
MBS2097527-03 0.1 mg

Recombinant Chymase 1, Mast Cell (CMA1)

Ask
View Details
Recombinant Chymase 1, Mast Cell (CMA1)
MBS2097527-04 0.2 mg

Recombinant Chymase 1, Mast Cell (CMA1)

Ask
View Details
Recombinant Chymase 1, Mast Cell (CMA1)
MBS2097527-05 0.5 mg

Recombinant Chymase 1, Mast Cell (CMA1)

Ask
View Details
Recombinant Chymase 1, Mast Cell (CMA1)
MBS2097527-06 1 mg

Recombinant Chymase 1, Mast Cell (CMA1)

Ask
View Details