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Anti-DUSP6/Mkp 3 Rabbit Monoclonal Antibody

Boster Bio Anti-DUSP6/Mkp 3 Rabbit Monoclonal Antibody catalog # M02157. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Dual specificity protein phosphatase 6;3.1.3.16;3.1.3.48; Dual specificity protein phosphatase PYST1; Mitogen-activated protein kinase phosphatase 3; MAP kinase phosphatase 3; MKP-3; DUSP6; MKP3, PYST1

Gene Name

DUSP6

Gene ID

1848

UniProt

Q16828

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human DUSP6

Clonality

Monoclonal

Clone

Clone: DBE-4

Tissue Specificity

Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.

Applications

WB, IHC, ICC, IF, IP, Flow Cytometry

Field of Research

Neural Signal Transduction, Neurology Process, Neuroscience

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Form

Liquid

Function

Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808) . Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

42320 MW

Observed Molecular Weight

73 kDa

Gene Name Synonym

Dual specificity protein phosphatase 6

Subcellular Location

Cytoplasm .

Protein Name

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Isotype

Rabbit IgG

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

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